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What is Ativan?
Ativan (lorazepam) belongs to a class of medications called benzodiazepines. It is thought that benzodiazepines work by enhancing the activity of certain neurotransmitters in the brain.
Ativan is used in adults and children at least 12 years old to treat anxiety disorders.
Ativan is also used to treat insomnia caused by anxiety or temporary situational stress.
Ativan is sometimes used to treat nausea and vomiting from cancer treatment and to control agitation caused by alcohol withdrawal.
Warnings
Ativan can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing. These effects can be fatal.
MISUSE OF ATIVAN CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep this medicine where others cannot get to it.
Lorazepam may be habit-forming and should be used only by the person it was prescribed for. Ativan should never be shared with another person, especially someone who has a history of drug abuse or addiction.
Do not stop using Ativan without asking your doctor. You may have life-threatening withdrawal symptoms if you stop using the medicine suddenly after long-term use. Some withdrawal symptoms may last up to 12 months or longer.
Get medical help right away if you stop using Ativan and have symptoms such as: unusual muscle movements, being more active or talkative, sudden and severe changes in mood or behavior, confusion, hallucinations, seizures, or thoughts about suicide.
Do not use Ativan if you are pregnant. Lorazepam can cause birth defects or life-threatening withdrawal symptoms in a newborn.
You should not use this medicine if you have narrow-angle glaucoma, severe respiratory insufficiency, myasthenia gravis, or if you are allergic to Valium or a similar medicine.
Before taking this medicine
You should not use Ativan if you have:
narrow-angle glaucoma; or
a history of allergic reaction to any benzodiazepine (lorazepam, alprazolam, diazepam, Valium, Xanax, Versed, Klonopin, and others).
To make sure Ativan is safe for you, tell your doctor if you have ever had:
asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder;
drug or alcohol addiction;
depression, mental illness or psychosis, mood changes, or suicidal thoughts or actions;
seizures;
an allergy to aspirin or yellow food dye; or
kidney or liver disease.
Tell your doctor if you are pregnant or plan to become pregnant. If you use Ativan during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of lorazepam on the baby.
You should not breastfeed.
If you do breastfeed, tell your doctor if you notice drowsiness, feeding problems, or slow weight gain in the nursing baby.
Ativan pregnancy and breastfeeding warnings (more detail)
How should I take Ativan?
Take Ativan exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides or instruction sheets. Never use Ativan in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to use more of this medicine.
Never share Ativan with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.
Do not stop using Ativan without asking your doctor. You may have life-threatening withdrawal symptoms if you stop using the medicine suddenly after long-term use.
Store Ativan tablets tightly closed at room temperature, away from moisture and heat.
Keep your medicine in a place where no one can use it improperly.
Ativan patient tips (more detail)
Dosing information
Usual Adult Dose for Anxiety:
Initial dose: 2 to 3 mg orally per day, given 2 to 3 times per day
Maintenance dose: 1 to 2 mg orally 2 to 3 times a day
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Uses:
-Management of anxiety disorders
-Short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
Usual Adult Dose for Insomnia:
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2 to 4 mg orally once a day at bedtime
Comments:
-The dosage should be increased gradually when needed to help avoid adverse effects.
-Clinical studies have not evaluated this drug for efficacy in long-term treatment (e.g., greater than 4 months).
Use: Management of insomnia due to anxiety of transient situational stress
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Usual Geriatric Dose for Anxiety:
Older or debilitated patients:
-Initial dose: 1 to 2 mg orally per day, given in divided doses
-Management of anxiety disorders
-Short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
Usual Pediatric Dose for Anxiety:
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12 years or older:
-Initial dose: 2 to 3 mg orally per day, given 2 to 3 times per day
-Maintenance dose: 1 to 2 mg orally 2 to 3 times a day
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-The daily dosage may vary from 1 to 10 mg/day.
-The dosage should be increased gradually when needed to help avoid adverse effects.
-When higher dosage is indicated, the evening dose should be increased before the daytime doses.
-Use of anxiolytic agents is typically not needed to treat anxiety/tension associated with the stress of everyday life.
-Clinical studies have not evaluated this drug for efficacy in long-term treatment (e.g., greater than 4 months).
Uses:
-Management of anxiety disorders
-Short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
Usual Pediatric Dose for Insomnia:12 years or older: 2 to 4 mg orally once a day at bedtime
Comments:
-For debilitated patients, an initial dosage of 1 to 2 mg/day in divided doses is recommended.
-The dosage should be increased gradually when needed to help avoid adverse effects.
-Clinical studies have not evaluated this drug for efficacy in long-term treatment (e.g., greater than 4 months).
Detailed Ativan dosage information
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of lorazepam can be fatal if you also drink alcohol or use other drugs that cause drowsiness or slow breathing.Overdose symptoms may include severe drowsiness, confusion, slurred speech, feeling restless, muscle weakness, loss of balance or coordination, feeling light-headed, slow heartbeats, weak or shallow breathing, or coma.
What should I avoid while taking Ativan?
Do not drink alcohol. Dangerous side effects or death could occur.
Avoid driving or hazardous activity until you know how Ativan will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Ativan side effects
Get emergency medical help if you have signs of an allergic reaction to Ativan: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Lorazepam can slow or stop your breathing, especially if you have recently used an opioid medication or alcohol. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
Ativan may cause serious side effects. Call your doctor at once if you have:
severe drowsiness;
unusual changes in mood or behavior, being agitated or talkative;
sudden restless feeling or excitement;
seizures, depression, thinking problems, thoughts of suicide or hurting yourself;
confusion, aggression, hallucinations;
sleep problems (insomnia);
vision changes; or
dark urine, or jaundice (yellowing of the skin or eyes).
Drowsiness or dizziness may last longer in older adults. Use caution to avoid falling or accidental injury.
Common Ativan side effects may include:
dizziness, sedation, drowsiness;
weakness; or
feeling unsteady.
You will need frequent blood tests to check your blood counts and liver function.
After you stop using Ativan, seek medical help right away if you have symptoms such as: unusual muscle movements, being more active or talkative, sudden and severe changes in mood or behavior, confusion, hallucinations, seizures, suicidal thoughts or actions.
Some withdrawal symptoms may last up to 12 months or longer after stopping Ativan suddenly. Tell your doctor if you have ongoing anxiety, depression, problems with memory or thinking, trouble sleeping, ringing in your ears, a burning or prickly feeling, or a crawling sensation under your skin.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Ativan side effects (more detail)
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What other drugs will affect Ativan?
Taking Ativan with other drugs that slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Tell your doctor about all your other medicines, especially:
valproate, probenecid, aminophylline, or theophylline;
medicine to treat mental illness; or
medicine that contains an antihistamine (such as sleep medicine, cold or allergy medicine).
This list is not complete and many other drugs may interact with lorazepam. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Ativan drug interactions (more detail)
Does Ativan interact with my other drugs?
Enter medications to view a detailed interaction report using our Drug Interaction Checker.
Drug name
Ativan
Add a drug to check interactions
Enter a drug name
Ingredients
Active ingredient: lorazepam
Inactive ingredients: lactose monohydrate, magnesium stearate, microcrystalline cellulose, and polacrilin potassium.
Manufacturer
Bausch Health US. LLC, Bridgewater, NJ 08807, US.
Popular FAQ
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Ativan Tablets (FDA)
Lorazepam (AHFS Monograph)
Other brands
Lorazepam Intensol, Ativan Injection, Loreev XR
Related treatment guides
Anxiety
Dysautonomia
ICU Agitation
Insomnia
Further information
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Ativan only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
Copyright 1996-2025 Cerner Multum, Inc. Version: 10.04.
Drug Status
Availability
Prescription only
Rx
Pregnancy & Lactation
Risk data available
CSA Schedule*
Some potential for abuse
4
Approval History
FDA approved 1977
10+years
User Reviews & Ratings
8.1 / 10
479 Reviews
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Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex (updated 9 Feb 2025), Cerner Multum™ (updated 3 Feb 2025), ASHP (updated 10 Feb 2025) and others. -
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What is Ambien?
Ambien is a sedative, also called a hypnotic. Ambien (zolpidem) affects chemicals in the brain that may be unbalanced in people with sleep problems (insomnia).
Ambien is used to treat insomnia. The immediate-release tablet is used to help you fall asleep when you first go to bed. The extended-release form, Ambien CR, which has a first layer that dissolves quickly to help you fall asleep, and a second layer that dissolves slowly to help you stay asleep.
Your doctor will determine which form of Ambien is best for you.
Warnings
Ambien may cause a severe allergic reaction. Stop taking this medicine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Do not share Ambien with another person, even if they have the same symptoms you have. The recommended doses of zolpidem are not the same in men and women, and this drug is not approved for use in children. Misuse of this medication can result in dangerous side effects.
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Ambien may impair your thinking or reactions. You may still feel sleepy the morning after taking this medicine, especially if you take the extended-release tablet, or if you are a woman. Wait at least 4 hours or until you are fully awake before you do anything that requires you to be awake and alert.
Never take Ambien in larger amounts or for longer than prescribed.
Do not take zolpidem if you have consumed alcohol during the day or just before bed.
Before taking this medicine
Some people using Ambien have engaged in activity such as driving, eating, walking, making phone calls, or having sex and later having no memory of the activity. If this happens to you, stop taking this medicine and talk with your doctor about another treatment for your sleep disorder.
You should not use Ambien if you are allergic to zolpidem. The tablets may contain lactose. Use caution if you are sensitive to lactose.
Ambien is not approved for use by anyone younger than 18 years old.
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Taking Ambien in the last 3 months of pregnancy may cause drowsiness or breathing problems in your newborn.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Ambien pregnancy and breastfeeding warnings (more detail)
How should I take Ambien?
Take Ambien exactly as prescribed by your doctor. Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed.
The recommended doses of zolpidem are not the same in men and women, and this drug is not approved for use in children.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
Zolpidem may be habit-forming. Misuse can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.
Do not share this medication with another person, even if they have the same symptoms you have. The recommended doses of Ambien are not the same in men and women, and this drug is not approved for use in children. Misuse of this medication can result in dangerous side effects.
Never take this medicine if you do not have a full 7 to 8 hours to sleep before being active again.
Ambien is for short-term use only. Tell your doctor if your insomnia symptoms do not improve, or if they get worse after using this medication for 7 to 10 nights in a row. Do not take this medicine for longer than 4 or 5 weeks without your doctor's advice.
Do not stop using Ambien suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using the medicine.
Insomnia symptoms may also return after you stop taking Ambien, and may be even worse than before. Call your doctor if you still have worsened insomnia for the first few nights after you stop taking this medicine.
Do not crush, chew, or break an Ambien CR tablet. Swallow the pill whole.
Store at room temperature away from moisture and heat. Do not freeze.
Detailed Ambien dosage information
What happens if I miss a dose?
Since Ambien is taken only at bedtime if needed, you are not likely to miss a dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of zolpidem can be fatal, especially when it is taken together with other medications that can cause drowsiness.
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What to avoid
Avoid taking Ambien during travel, such as to sleep on an airplane. You may be awakened before the effects of the medicine have worn off. Amnesia (forgetfulness) is more common if you do not get a full 7 to 8 hours of sleep after taking Ambien.
Avoid driving or hazardous activity until you know how zolpidem will affect you. You may still feel sleepy the morning after taking Ambien, and your reactions could be impaired. Wait until you are fully awake before you drive, operate machinery, pilot an airplane, or do anything that requires you to be awake and alert.
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Do not take this medicine if you have consumed alcohol during the day or just before bed.
Ambien side effects
Zolpidem may cause a severe allergic reaction. Stop taking Ambien and get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Report any new or worsening symptoms to your doctor, such as: depression, anxiety, aggression, agitation, confusion, unusual thoughts, hallucinations, memory problems, changes in personality, risk-taking behavior, decreased inhibitions, no fear of danger, or thoughts of suicide or hurting yourself.
Stop using this medicine and call your doctor at once if you have:
chest pain, fast or irregular heartbeat, feeling short of breath;
trouble breathing or swallowing; or
feeling like you might pass out.
The sedative effect of Ambien may be stronger in older adults.
Dizziness or severe drowsiness can cause falls, accidents, or severe injuries.
Common Ambien side effects may include:
daytime drowsiness, dizziness, weakness, feeling "drugged" or light-headed;
tired feeling, loss of coordination;
stuffy nose, dry mouth, nose or throat irritation;
nausea, constipation, diarrhea, upset stomach; or
headache, muscle pain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Ambien side effects (more detail)
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What other drugs will affect Ambien?
Using Ambien with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Many drugs can interact with zolpidem, making it less effective or increasing side effects. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.
Ambien drug interactions (more detail)
Does Ambien interact with my other drugs?
Enter medications to view a detailed interaction report using our Drug Interaction Checker.
Drug name
Ambien
Add a drug to check interactions
Enter a drug name
Popular FAQ
Why am I unable to sleep after taking Ambien?
Quviviq vs. Ambien: How do they compare?
Is Ambien safe for long-term use?
Ambien: What are 11 Things You Need to Know?
Xanax vs Ambien: How do they compare?
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Lunesta vs Ambien: How do they compare?
Is Ambien a benzo?
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Drug class: miscellaneous anxiolytics, sedatives and hypnotics
Breastfeeding
En español
Patient resources
Other brands
Zolpimist, Intermezzo, Edluar
Professional resources
Ambien prescribing information
Zolpidem (AHFS Monograph)
Other brands
Zolpimist, Intermezzo, Edluar
Other formulations
Ambien CR
Related treatment guides
Insomnia
Further information
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Ambien only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
Copyright 1996-2025 Cerner Multum, Inc. Version: 13.03.
Drug Status
Availability
Prescription only
Rx
Pregnancy & Lactation
Risk data available
CSA Schedule*
Some potential for abuse
4
Approval History
FDA approved 1992
10+years
User Reviews & Ratings
7.1 / 10
558 Reviews
Related News
What Do Sleep Medications Do to Your Brain?
Images
Pill AMB 5 5401 is Ambien 5 mg
Ambien 5 mg (AMB 5 5401)
Ambien 5 mg (AMB 5 5401)
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Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex (updated 9 Feb 2025), Cerner Multum™ (updated 3 Feb 2025), ASHP (updated 10 Feb 2025) and others.
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