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Ativan (lorazepam) belongs to a class of medications called benzodiazepines. It is thought that benzodiazepines work by enhancing the activity of certain neurotransmitters in the brain.
Ativan is used in adults and children at least 12 years old to treat anxiety disorders.
Ativan is also used to treat insomnia caused by anxiety or temporary situational stress.
Ativan is sometimes used to treat nausea and vomiting from cancer treatment and to control agitation caused by alcohol withdrawal.
Warnings
Ativan can slow or stop your breathing, especially if you have recently used an opioid medication,
alcohol, or other drugs that can slow your breathing. These effects can be fatal.
MISUSE OF ATIVAN CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep this medicine where others cannot get to it.
Lorazepam may be habit-forming and should be used only by the person it was prescribed for. Ativan should never be shared with another person, especially someone who has a history of drug abuse or addiction.
Do not stop using Ativan without asking your doctor. You may have life-threatening withdrawal symptoms if you stop using the medicine suddenly after long-term use. Some withdrawal symptoms may last up to 12 months or longer.
Get medical help right away if you stop using Ativan and have symptoms such as: unusual muscle movements, being more active or talkative, sudden and severe changes in mood or behavior, confusion, hallucinations, seizures, or thoughts about suicide.
Do not use Ativan if you are pregnant. Lorazepam can cause birth defects or life-threatening withdrawal symptoms in a newborn.
You should not use this medicine if you have narrow-angle glaucoma, severe respiratory insufficiency, myasthenia gravis, or if you are allergic to Valium or a similar medicine.
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Ativan (lorazepam) belongs to a class of medications called benzodiazepines. It is thought that benzodiazepines work by enhancing the activity of certain neurotransmitters in the brain.
Ativan is used in adults and children at least 12 years old to treat anxiety disorders.
Ativan is also used to treat insomnia caused by anxiety or temporary situational stress.
Ativan is sometimes used to treat nausea and vomiting from cancer treatment and to control agitation caused by alcohol withdrawal.
Warnings
Ativan can slow or stop your breathing, especially if you have recently used an opioid medication,
alcohol, or other drugs that can slow your breathing. These effects can be fatal.
MISUSE OF ATIVAN CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep this medicine where others cannot get to it.
Lorazepam may be habit-forming and should be used only by the person it was prescribed for. Ativan should never be shared with another person, especially someone who has a history of drug abuse or addiction.
Do not stop using Ativan without asking your doctor. You may have life-threatening withdrawal symptoms if you stop using the medicine suddenly after long-term use. Some withdrawal symptoms may last up to 12 months or longer.
Get medical help right away if you stop using Ativan and have symptoms such as: unusual muscle movements, being more active or talkative, sudden and severe changes in mood or behavior, confusion, hallucinations, seizures, or thoughts about suicide.
Do not use Ativan if you are pregnant. Lorazepam can cause birth defects or life-threatening withdrawal symptoms in a newborn.
You should not use this medicine if you have narrow-angle glaucoma, severe respiratory insufficiency, myasthenia gravis, or if you are allergic to Valium or a similar medicine.
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Zolpidem is a medication that treats insomnia. It works by helping you get to sleep faster. It also helps you stay asleep throughout the night. You should only use this medication for a short period of time. The brand name of zolpidem is Ambien®.
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What is this medication?
ZOLPIDEM (zole PI dem) treats insomnia. It helps you get to sleep faster and stay asleep throughout the night. It is often used for a short period of time.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Ambien
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
Depression
History of drug abuse or addiction
If you often drink alcohol
Liver disease
Lung or breathing disease
Myasthenia gravis
Sleep apnea
Sleep-walking, driving, eating or other activity while not fully awake after taking a sleep medication
Suicidal thoughts, plans, or attempt; a previous suicide attempt by you or a family member
An unusual or allergic reaction to zolpidem, other medications, foods, dyes, or preservatives
Pregnant or trying to get pregnant
Breast-feeding
How should I use this medication?
Take this medication by mouth with a glass of water. Follow the directions on the prescription label. It is better to take this medication on an empty stomach and only when you are ready for bed. Do not take your medication more often than directed. If you have been taking this medication for several weeks and suddenly stop taking it, you may get unpleasant withdrawal symptoms. Your care team may want to gradually reduce the dose. Do not stop taking this medication on your own. Always follow your care team's advice.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your care team regarding the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
This does not apply. This medication should only be taken immediately before going to sleep. Do not take double or extra doses.
What may interact with this medication?
Alcohol
Antihistamines for allergy, cough and cold
Certain medications for anxiety or sleep
Certain medications for depression, like amitriptyline, fluoxetine, sertraline
Certain medications for fungal infections like ketoconazole and itraconazole
Certain medications for seizures like phenobarbital, primidone
Ciprofloxacin
Dietary supplements for sleep, like valerian or kava kava
General anesthetics like halothane, isoflurane, methoxyflurane, propofol
Local anesthetics like lidocaine, pramoxine, tetracaine
Medications that relax muscles for surgery
Narcotic medications for pain
Phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
Rifampin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular checks on your progress. Keep a regular sleep schedule by going to bed at about the same time each night. Avoid caffeine-containing drinks in the evening hours. When sleep medications are used every night for more than a few weeks, they may stop working. Talk to your care team if you still have trouble sleeping.
After taking this medication, you may get up out of bed and do an activity that you do not know you are doing. The next morning, you may have no memory of this. Activities include driving a car ("sleep-driving"), making and eating food, talking on the phone, sexual activity, and sleep-walking. Serious injuries have occurred. Stop the medication and call your care team right away if you find out you have done any of these activities. Do not take this medication if you have used alcohol that evening. Do not take it if you have taken another medication for sleep. The risk of doing these sleep-related activities is higher.
Wait for at least 8 hours after you take a dose before driving or doing other activities that require full mental alertness. Do not take this medication unless you are able to stay in bed for a full night (7 to 8 hours) before you must be active again. You may have a decrease in mental alertness the day after use, even if you feel that you are fully awake. Tell your care team if you will need to perform activities requiring full alertness, such as driving, the next day. Do not stand or sit up quickly after taking this medication, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
If you or your family notice any changes in your behavior, such as new or worsening depression, thoughts of harming yourself, anxiety, other unusual or disturbing thoughts, or memory loss, call your care team right away.
After you stop taking this medication, you may have trouble falling asleep. This is called rebound insomnia. This problem usually goes away on its own after 1 or 2 nights.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Change in vision such as blurry vision, seeing halos around lights, vision loss
CNS depression—slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, difficulty staying awake
Mood and behavior changes—anxiety, nervousness, confusion, hallucinations, irritability, hostility, thoughts of suicide or self-harm, worsening mood, feelings of depression
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Ambien is a sedative, also called a hypnotic. Ambien (zolpidem) affects chemicals in the brain that may be unbalanced in people with sleep problems (insomnia).
Ambien is used to treat insomnia. The immediate-release tablet is used to help you fall asleep when you first go to bed. The extended-release form, Ambien CR, which has a first layer that dissolves quickly to help you fall asleep, and a second layer that dissolves slowly to help you stay asleep.
Your doctor will determine which form of Ambien is best for you.
Warnings
Ambien may cause a severe allergic reaction. Stop taking this medicine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Do not share Ambien with another person, even if they have the same symptoms you have. The recommended doses of zolpidem are not the same in men and women, and this drug is not approved for use in children. Misuse of this medication can result in dangerous side effects.
Ambien may impair your thinking or reactions. You may still feel sleepy the morning after taking this medicine, especially if you take the extended-release tablet, or if you are a woman. Wait at least 4 hours or until you are fully awake before you do anything that requires you to be awake and alert.
Never take Ambien in larger amounts or for longer than prescribed.
Do not take zolpidem if you have consumed alcohol during the day or just before bed.
Before taking this medicine
Some people using Ambien have engaged in activity such as driving, eating, walking, making phone calls, or having sex and later having no memory of the activity. If this happens to you, stop taking this medicine and talk with your doctor about another treatment for your sleep disorder.
You should not use Ambien if you are allergic to zolpidem. The tablets may contain lactose. Use caution if you are sensitive to lactose.
Ambien is not approved for use by anyone younger than 18 years old.
To make sure this medicine is safe for you, tell your doctor if you have ever had:
depression, mental illness, or suicidal thoughts;
drug or alcohol addiction;
lung disease or breathing problems;
sleep apnea (breathing stops during sleep); or
liver or kidney disease.
Taking Ambien in the last 3 months of pregnancy may cause drowsiness or breathing problems in your newborn.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Ambien pregnancy and breastfeeding warnings (more detail)
How should I take Ambien?
Take Ambien exactly as prescribed by your doctor. Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed.
The recommended doses of zolpidem are not the same in men and women, and this drug is not approved for use in children.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
Zolpidem may be habit-forming. Misuse can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.
Do not share this medication with another person, even if they have the same symptoms you have. The recommended doses of Ambien are not the same in men and women, and this drug is not approved for use in children. Misuse of this medication can result in dangerous side effects.
Never take this medicine if you do not have a full 7 to 8 hours to sleep before being active again.
Ambien is for short-term use only. Tell your doctor if your insomnia symptoms do not improve, or if they get worse after using this medication for 7 to 10 nights in a row. Do not take this medicine for longer than 4 or 5 weeks without your doctor's advice.
Do not stop using Ambien suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using the medicine.
Insomnia symptoms may also return after you stop taking Ambien, and may be even worse than before. Call your doctor if you still have worsened insomnia for the first few nights after you stop taking this medicine.
Do not crush, chew, or break an Ambien CR tablet. Swallow the pill whole.
Store at room temperature away from moisture and heat. Do not freeze.
Detailed Ambien dosage information
What happens if I miss a dose?
Since Ambien is taken only at bedtime if needed, you are not likely to miss a dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of zolpidem can be fatal, especially when it is taken together with other medications that can cause drowsiness.
Overdose symptoms may include sleepiness, confusion, shallow breathing, feeling light-headed, fainting, or coma.
What to avoid
Avoid taking Ambien during travel, such as to sleep on an airplane. You may be awakened before the effects of the medicine have worn off. Amnesia (forgetfulness) is more common if you do not get a full 7 to 8 hours of sleep after taking Ambien.
Avoid driving or hazardous activity until you know how zolpidem will affect you. You may still feel sleepy the morning after taking Ambien, and your reactions could be impaired. Wait until you are fully awake before you drive, operate machinery, pilot an airplane, or do anything that requires you to be awake and alert.
Do not take this medicine if you have consumed alcohol during the day or just before bed.
Ambien side effects
Zolpidem may cause a severe allergic reaction. Stop taking Ambien and get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Report any new or worsening symptoms to your doctor, such as: depression, anxiety, aggression, agitation, confusion, unusual thoughts, hallucinations, memory problems, changes in personality, risk-taking behavior, decreased inhibitions, no fear of danger, or thoughts of suicide or hurting yourself.
Stop using this medicine and call your doctor at once if you have:
chest pain, fast or irregular heartbeat, feeling short of breath;
trouble breathing or swallowing; or
feeling like you might pass out.
The sedative effect of Ambien may be stronger in older adults.
Dizziness or severe drowsiness can cause falls, accidents, or severe injuries.
Common Ambien side effects may include:
daytime drowsiness, dizziness, weakness, feeling "drugged" or light-headed;
tired feeling, loss of coordination;
stuffy nose, dry mouth, nose or throat irritation;
nausea, constipation, diarrhea, upset stomach; or
headache, muscle pain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Using Ambien with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Many drugs can interact with zolpidem, making it less effective or increasing side effects. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.
Ambien drug interactions (more detail)
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Ambien is a sedative, also called a hypnotic. Ambien (zolpidem) affects chemicals in the brain that may be unbalanced in people with sleep problems (insomnia).
Ambien is used to treat insomnia. The immediate-release tablet is used to help you fall asleep when you first go to bed. The extended-release form, Ambien CR, which has a first layer that dissolves quickly to help you fall asleep, and a second layer that dissolves slowly to help you stay asleep.
Your doctor will determine which form of Ambien is best for you.
Warnings
Ambien may cause a severe allergic reaction. Stop taking this medicine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Do not share Ambien with another person, even if they have the same symptoms you have. The recommended doses of zolpidem are not the same in men and women, and this drug is not approved for use in children. Misuse of this medication can result in dangerous side effects.
Ambien may impair your thinking or reactions. You may still feel sleepy the morning after taking this medicine, especially if you take the extended-release tablet, or if you are a woman. Wait at least 4 hours or until you are fully awake before you do anything that requires you to be awake and alert.
Never take Ambien in larger amounts or for longer than prescribed.
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Uses
What is alprazolam used for?
Alprazolam is commonly used to treat the following conditions.
Anxiety
Panic disorder with or without the fear of open spaces, also called agoraphobia
Alprazolam may also be used for other conditions as determined by your healthcare provider.
How does alprazolam work (mechanism of action)?
Alprazolam produces a calming effect on the brain, which helps to reduce anxiety and promote relaxation.
How is alprazolam supplied (dosage forms)?
Brands and other names
Xanax
Xanax XR
Dosage forms and strengths
1 mg/mL oral solution
0.5 mg, 1mg, 2 mg, 3 mg extended-release oral tablets
0.25 mg, 0.5 mg, 1mg, 2 mg oral tablets
How should I store alprazolam?
Oral Tablet. Alprazolam tablets should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C), for shorter periods of time, such as when transporting it. Store in a cool, dry place. Some tablets need to be protected from light. Ask your healthcare provider if you have any questions about how to store your medicine.
Oral Liquid. Alprazolam solution should be stored at room temperature, between 68 F to 77 F (20 C to 25
C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C), for shorter periods of time, such as when transporting it. Store in a cool, dry place. Protect from light. Throw away 90 days after opening the bottle. You can write the date on the bottle the day you open it as a reminder.
Side Effects
What are the most common side effects of alprazolam?
The most common side effects of alprazolam are listed below. Tell your healthcare provider if you have any of these side effects that bother you.
Trouble with balance or coordination
Low blood pressure
Trouble saying words clearly (dysarthria)
Changes in sex drive
Problems with memory
Drowsiness
Constipation or nausea
There may be other side effects of alprazolam that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.
What are the serious side effects of alprazolam?
While less common, the most serious side effects of alprazolam are described below, along with what to do if they happen.
Severe Allergic Reactions. Alprazolam can cause allergic reactions, which can be serious. Stop taking alprazolam and get help right away if you have any of the following symptoms of a serious allergic reaction.
Breathing problems or wheezing
Racing heart
Fever or general ill feeling
Swollen lymph nodes
Swelling of the face, lips, mouth, tongue, or throat
Trouble swallowing or throat tightness
Itching, skin rash, or pale red bumps on the skin called hives
Nausea or vomiting
Dizziness, feeling lightheaded, or fainting
Stomach cramps
Joint pain
Risk of Misuse and Addiction. Misusing alprazolam can lead to serious side effects like coma or death. Misuse means taking a medicine in a way other than how it was prescribed. Take alprazolam exactly as prescribed. Tell your healthcare provider if you feel that alprazolam is not working. Call your healthcare provider right away or go to the nearest emergency room if you have any of the following serious symptoms.
Sudden confusion or feeling disoriented
Feeling paranoid
Suicidal thoughts or actions
Seizures
Trouble breathing
Dependence and Withdrawal Reactions. Alprazolam can cause physical dependence, which means your body relies on the medicine to function properly. If you stop alprazolam suddenly, it could lead to withdrawal symptoms, which may be life-threatening. Do not stop taking alprazolam without talking with your healthcare provider. Your healthcare provider will tell you how to stop alprazolam to reduce the
risk of withdrawal reactions. Call your healthcare provider right away or go to the nearest emergency room if you have any of the following serious symptoms.
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Do not stop using Xanax without asking your doctor. You may have life-threatening withdrawal symptoms if you stop using the medicine suddenly after long-term use. Some withdrawal symptoms may last up to 12 months or longer.
Get medical help right away if you stop using Xanax and have symptoms such as: unusual muscle movements, being more active or talkative, sudden and severe changes in mood or behavior, confusion, hallucinations, seizures, or thoughts about suicide.
Xanax is a federal controlled substance (C-IV) because it can be abused or lead to dependence. Keep this medicine in a safe place to prevent misuse and abuse. Selling or giving away this Xanax may harm others, and is against the law. Tell your healthcare provider if you have abused or been dependent on alcohol, prescription medicines or street drugs.
Before taking this medicine
You should not take Xanax if:
you also take antifungal medicine such as itraconazole or ketoconazole; or
you have a history of allergic reaction to any benzodiazepine (alprazolam, lorazepam, diazepam, Ativan, Valium, Versed, Klonopin, and others).
To make sure Xanax is safe for you, tell your doctor if you have ever had:
breathing problems;
drug or alcohol addiction;
depression, mood problems, or suicidal thoughts or behavior; or
kidney or liver disease.
Tell your doctor if you are pregnant or plan to become pregnant. If you use Xanax during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.
You should not breastfeed.
If you do breastfeed, tell your doctor if you notice drowsiness or feeding problems in the baby.
Not approved for use by anyone younger than 18 years old.
Xanax pregnancy and breastfeeding warnings (more detail)
How should I take Xanax?
Take Xanax exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides or instruction sheets. Never use Xanax in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to use more of this medicine.
Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.
Swallow the Xanax XR extended-release tablet whole. Do not crush, chew, or break the tablet.
Call your doctor if your symptoms do not improve, or if they get worse.
If you use this medicine long-term, you may need frequent medical tests.
Do not stop using Xanax without asking your doctor. You may have life-threatening withdrawal symptoms if you stop using the medicine suddenly after long-term use.
Store Xanax at room temperature away from moisture, heat, and light. Keep your medicine in a place where no one can use it improperly.
Dosing information
Usual Adult Dose for Anxiety:
Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day
-Maximum dose: 4 mg/day
Usual Adult Dose for Panic Disorder:
Immediate-release tablets: 0.5 mg orally administered 3 times a day
-Maximum dose: 10 mg/day
Extended-release tablets:
-Initial dose: 0.5 to 1 mg orally once a day
-Maintenance dose: 3 to 6 mg orally per day, preferably in the morning
-Maximum dose: 10 mg/day
Comments:
-The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently.
-Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.
-The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction.
-The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day.
-The times of administration should be distributed as evenly as possible throughout the waking hours.
Usual Geriatric Dose for Anxiety:
Elderly or debilitated patients:
Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.
Usual Geriatric Dose for Panic Disorder:
Elderly or debilitated patients:
Immediate-release tablets:
-Initial dose: 0.25 mg orally administered 2 or 3 times a day
Extended-release tablets:
-Initial dose: 0.5 mg orally once a day
Comments:
-If side effects develop, the dose may be lowered.
-The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently.
-Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.
Detailed Xanax dosage information
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal if you take it with alcohol, opioid medicine, or other drugs that cause drowsiness or slow your breathing.
Overdose symptoms may include severe drowsiness, confusion, slurred speech, muscle weakness, loss of balance or coordination, feeling light-headed, slow heartbeats, weak or shallow breathing, fainting, or coma.
What should I avoid while taking Xanax?
Avoid drinking alcohol. Dangerous side effects or death could occur.
Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Xanax side effects
Get emergency medical help if you have signs of an allergic reaction to Xanax: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Alprazolam can slow or stop your breathing, especially if you have recently used an opioid medication or alcohol. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
Common side effects of Xanax may include:
drowsiness; or
feeling light-headed.
Xanax may cause serious side effects. Call your doctor at once if you have:
weak or shallow breathing;
a light-headed feeling, like you might pass out;
a seizure;
hallucinations, risk-taking behavior;
increased energy, decreased need for sleep;
racing thoughts, being agitated or talkative;
double vision; or
jaundice (yellowing of the skin or eyes).
Drowsiness or dizziness may last longer in older adults. Use caution to avoid falling or accidental injury.
After you stop using Xanax, get medical help right away if you have symptoms such as: unusual muscle movements, being more active or talkative, sudden and severe changes in mood or behavior, confusion, hallucinations, seizures, suicidal thoughts or actions.
Some withdrawal symptoms may last up to 12 months or longer after stopping this medicine suddenly. Tell your doctor if you have ongoing anxiety, depression, problems with memory or thinking, trouble sleeping, ringing in your ears, a burning or prickly feeling, or a crawling sensation under your skin.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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What other drugs will affect Xanax?
Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.
Taking Xanax with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Many drugs can interact with alprazolam, and some drugs should not be used at the same time. Tell your doctor about all other medicines you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.
Xanax drug interactions (more detail)
Does Xanax interact with my other drugs?
Enter medications to view a detailed interaction report using our Drug Interaction Checker.
Drug name
Xanax
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Xanax only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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Copyright 1996-2025 Cerner Multum, Inc. Version: 13.02.
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8.6 / 10
912 Reviews
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What is Xanax?
Xanax is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.
Xanax is used to treat anxiety disorders and anxiety caused by depression.
Xanax is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).
It is dangerous to purchase Xanax on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.
Warnings
Xanax can slow or stop your breathing, especially if you have recently used an opioid medication or alcohol.
MISUSE OF XANAX CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it.