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Tapentadol is a prescription opioid analgesic used for the treatment of moderate to severe pain. It works through dual mechanisms: binding to µ-opioid receptors and inhibiting norepinephrine re uptake, which enhances its analgesic effects. This unique action makes it effective for both nociceptive and neuropathic pain. Tapentadol is available in immediate-release and extended-release formulations, the latter being prescribed for chronic pain requiring long-term management.